ABSTRACT
There is a paucity of knowledge about prenatal and perinatal risks through maternal
amatoxin poisoning. No symptoms of amatoxin intoxication, except for a slight temporary
increase in liver enzymes activity, occurred in a term newborn after delivery despite
an Amanita phalloides intoxication of the mother 2 days before. Considering previous reports, severe fetal
intoxication may not occur during the entire pregnancy.
KEYWORDS
Amanita phalloides
- poisoning - pregnancy - fetal risk
REFERENCES
- 1
Persson H E, Sjöberg G K, Haines J A, Pronczuk de Garbino J.
Poison severity score. Grading of acute poisoning.
J Toxicol Clin Toxicol.
1998;
36
205-213
- 2 Nicholson J F, Pesce M A.
Reference Ranges for Laboratory Tests and Procedures. In: Behrman RE, Kliegman RM, and Jenson HB Nelson Textbook of Pediatrics, 17th ed. Philadelphia;
Saunders 2004: 2400-2407
- 3 Bühlmann Laboratories .Amanitin ELISA Instruction Manual. Allschwil, Switzerland;
Bühlmann Laboratories 2000
- 4
Staak R F, Maurer H H.
New Bühlmann ELISA for determination of amanitins in urine—are there false positive
results due to interferences with urine matrix, drugs or their metabolites?.
Toxichem und Krimtech.
2001;
68
68-71
- 5
Jaeger A, Jehl F, Sauder P, Kopferschmitt J.
Kinetics of amatoxins in human poisoning: therapeutic implications.
J Toxicol Clin Toxicol.
1993;
31
63-80
- 6
Riethmüller J, Tomaske M, Bosk A, Gerhardt E, Amon O, Niethammer D.
Therapie der häufigsten Pilzvergiftungen.
Monatsschr Kinderheilkd.
2004;
152
892-901
- 7
Boyer J C, Hernandez F, Esorc J, De la Coussaye J E, Bali J P.
Management of maternal Amanita phalloides poisoning during the first trimester of
pregnancy: a case report and review of the literature.
Clin Chem.
2001;
47
971-974
- 8
Nagy I, Pogatsa-Murray G, Zlanyi S, Komlosi P, Laszlo F, Ungi I.
Amanita poisoning during second trimester of pregnancy.
Clin Investig.
1994;
72
794-798
- 9
Wu B F, Wang M M.
Molecular absorbent recirculating system in dealing with maternal Amanita poisoning
during the second pregnancy trimester: a case report.
Hepatobiliary Pancreat Dis Int.
2004;
3
152-154
- 10
Jaros F, Kascak M.
Incidence and current treatment of cytotoxic cyclopeptide (phalloidine) poisoning
in pregnant women.
Vnitr Lek.
1996;
42
414-417
, Abstract
- 11
Dolfi F, Gonnella R.
Acute amanita phalloides poisoning in the second pregnancy trimester.
Minerva Anestesiol.
1994;
60
153-154
- 12
Schleufe P, Seidel C.
Knollenblätterpilz-Intoxikation in der Schwangerschaft.
, [Amanita poisoning during pregnancy]
Anästhesiol Intensivmed Notfallmed Schmerzther.
2003;
38
716-718
- 13
Timar L, Czeizel A E.
Birth weight and congenital anomalies following poisonous mushroom intoxication during
pregnancy.
Reprod Toxicol.
1997;
11
861-866
- 14
Belliardo F, Massano G, Accomo S.
Amatoxins do not cross the placental barrier.
Lancet.
1983;
1
1381
- 15
Kaufmann M, Müller A, Paweletz N, Haller U, Kubli F.
Fetal damage due to mushroom poisoning with amanita phalloides during the first trimester
of pregnancy.
Geburtshilfe Frauenheilkd.
1978;
38
122-124
- 16
Stickel F, Egerer G, Seitz H K.
Hepatotoxicity of botanicals.
Public Health Nutr.
2000;
3
113-124
- 17
Fineschi V, Di Paolo M, Centini F.
Histological criteria for diagnosis of amanita phalloides poisoning.
J Forensic Sci.
1996;
41
429-432
Rangmar GoelzM.D.
Department of Neonatology, University Children's Hospital Tuebingen
Calwerstr. 7, D-72076 Tuebingen Germany
Email: Rangmar.Goelz@med.uni-tuebingen.de
